GPX1 Boost Ingredients

The GPX-1 SNP is supported by extra selenium with other ingredients that specifically scavenge hydrogen peroxide radicals and/or help increase glutathione peroxidase activity.


  • GPX-1 is a seleniumprotein, meaning it incorporates selenium into its protein structure. It has been established that selenium deficiencies reduce GPX-1 activity.26,27


Citrus Bioflavonoids (Naringin, Hesperidin)

  • Naringin has been shown to suppress DNA damage induced by hydrogen peroxide.18
  • Hesperidin has been shown to protect against the damaging effects of hydrogen peroxide.19,20

Ginkgo leaf and Astragulus Root

  • Specific activity against hydrogen peroxide-induced lipid peroxidation and cell death.21,22

Milk Thistle

  • Silymarin reduces oxidative stress caused by hydrogen peroxide as well as increases the antioxidant activity of various antioxidant enzymes including GPX1.23

Anthocyanins (from blueberries, black currants, and grapes)

  • An enormous amount of research confirms the antioxidant activity of anthocyanins. These include promoting cardiovascular health, and protection against oxidative stress.

Tumeric Extract (Curcumin)

  • Dietary curcumin has shown to enhance serum GPX activity and lower blood lipid peroxide levels in animals.24

Alpha Lipoic Acid

  • Animal studies have shown that dietary alpha lipoic acid supplementation increases GPX activity.25,26


  • 18. Kanno S, et al. J Pharmacol Sci. 2003 Jun;92(2):166-70.
  • 19. Chen MC, et al. J Agric Food Chem. 2010 Mar 24;58(6):3330-5.
  • 20. Kalpana KB, et al. Mol Cell Biochem. 2009 Mar;323(1-2):21-9.
  • 21. Sarikcioglu SB, et al. Phytother Res. 2004. 18(10):837-40.
  • 22. Wang D, et al. Zhongguo Zong Yao Za Zhi. 1996. 21(12):746-8.
  • 23. Kiruthiga PV, et al. Chemosphere. 2007. 68(8):1511-8.
  • 24. Manjunatha H, et al. Lipids. 2007. 42(12):1133-42.
  • 25. Martim AC, et al. J Nutr Biochem. 2003. 14(5):288-94.
  • 26. El Midaoui A, et al. Hypertension. 2002. 39(2):303-307.

This information is for educational purposes only. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.


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