SOD2 Boost Ingredients

The SOD2 SNP is supported by antioxidant ingredients with specific activity against the superoxide radical as well as helping increase mSOD activity.

Green Tea and White Tea Extracts (Polyphenols, Catechins)

  • The potent antioxidant activity of these teas has been supported in epidemiological studies, cellular research and animal studies.
  • Tea catechins have shown direct scavenging activity against superoxide radicals.11,12
  • Epigallocatechin-3-gallate (EGCG), the major catechin found in tea extracts, was shown to specifically augment the activity of superoxide dismutase, as well as reduce oxidative stress in animal studies.13
  • Enhancement of superoxide dismutase activity combined with reduction of superoxide radical concentration was seen in heart tissue of animals supplemented with tea catechins.14

Bilberry Extract (Anthocyanins)

  • Anthocyanins found in bilberry have known superoxide scavenging activity.15


  • Spirulina contains a relatively high level of superoxide dismutase.16
  • Phycocyanin, the main plant pigment found in spirulina, has been shown to significantly decrease cardiac production of the superoxide anion in animal studies.17

Niacin (Vitamin B3)

  • Nicotinamide, a derivative of niacin, is required by the body for the production of certain coenzymes essential for proper functioning of superoxide dismutase.


  • 11. Nakagawa T, et al. Food Chem Toxicol. 2002. 40(12):1745-50.
  • 12. Pillai SP, et al. J. Environ Pathol Toxico Oncol. 1999. 18(3):147-158.
  • 13. Srividhya R, et al. Int J Dev Neurosci. 2008. 26(2):217-23.
  • 14. Kim, MJ, et al. J Med Food. 2004. 7(3):299-304.
  • 15. Rahman MM, et al. Free Radic Res. 2006. 40(9):993-1002.
  • 16. Belay A, et al. The Journal of the American Nutraceutical Association. 2002. 5(2):27-48.
  • 17. Riss J, et al. J Agric Food Chem. 2007. 55(19):7962-7.

This information is for educational purposes only. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.


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